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Bioinformatic > Signal Sequence (leader Sequence)

The following information is about Signal Sequence (leader Sequence).

Signal Sequence (leader Sequence) Defined

A short sequence added to the amino-terminal end of a polypeptide chain that forms an amphipathic helix allowing the nascent polypeptide to migrate through membranes such as the endoplasmic reticulum or the cell membrane. It is cleaved from the polypeptide after the protein has crossed the membrane.

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