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Off-site Regulatory Gene Links, User Submitted

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Tue Oct 28

• "Loss of putative tumor suppressor EI24/PIG8 confers resistance to etoposide.": "rget gene EI24/PIG8 is lost in invasive breast cancers,sugges ting that EI24/PIG8 is a tumor suppressor that prevents tumor spreading, and partially mediates p53-attributed tumor suppressor activity. EI24/PIG8 also has pro-apoptotic activity indicating that loss of EI24/PIG8 may modulate sensitivity to chemotherapy. Here it is demonstrated that suppression of EI24/PIG8 in fibroblasts and breast cancer cells significantly inhibits the apoptotic response to etoposide treatment. These findings suggest that loss of EI24/PIG8 contributes significantly to resistance of cells to chemotherapeut ic agents that function through p53, and identify the EI24/PIG8 status as a potentially new prognostic marker of chemotherapy responsiveness ."

Mon Jul 28

• geard04modelli ng.pdf (application/p df Object)

Wed Jun 18

• Inferring gene regulatory networks from time series data using the minimum description length principle -- Zhao et al. 22 (17): 2129 -- Bioinformatics

Mon Feb 18

• Research Projects at the Center for Cell Dynamics

Wed Jan 16

• Project: Gene Networks in Embryo Pattern Formation and Regulatory Dynamics

Fri Sep 14

• Regulatory Sequence Analysis Tools (RSAT)

Mon Feb 26

• PyBioS

Tue Jan 9

• The DREAM Project | Assessing the Accuracy of Reverse Engineering Methods

Wed Nov 8

• From the Cover: A genetic variant that disrupts MET transcription is associated with autism -- Campbell et al. 103 (45): 16834 -- Proceedings of the National Academy of Sciences

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