|
 |
Bioinformatic > Homology
The following information is about Homology.
Homology Defined
(strict) Two or more biological species, systems or molecules that share a common evolutionary ancestor. (general) Two or more gene or protein sequences that share a significant degree of similarity, typically measured by the amount of identity (in the case of DNA), or conservative replacements (in the case of protein), that they register along their lengths. Sequence "homology" searches are typically performed with a query DNA or protein sequence to identify known genes or gene products that share significant similarity and hence might inform on the ancestry, heritage and possible function of the query gene.
This definition is in context to Bioinformatic. See more contextual defintions for Homology.
Are you looking for additional Bioinformatic > Homology news? Try our new "Homology News Focus" area.
Off-site Homology Links, User Submitted
The following links have been collected through user bookmark submission in the Homology category. Please note, because these resources are off-site we cannot guarantee the accuracy or quality of any information.
Tue Nov 25
- OrthoMCL Database Home: Orthologs are homologs seperated by speciation events. Paralogs are homologs separated by duplication events. OrthoMCL is a genome-scale algorithm for grouping orthologous protein sequences. It provides not only groups shared by two or more species/genome s, but also groups representing species-specif ic gene expansion families. So it serves as an important utility for automated eukaryotic genome annotation. OrthoMCL starts with reciprocal best hits within each genome as putative in-paralog/rec ent paralog pairs and reciprocal best hits across any two genomes as putative ortholog pairs. Related proteins are interlinked in a similarity graph. Then MCL (Markov Clustering algorithm,Van Dongen 2000; www.micans.org /mcl) is invoked to split mega-clusters. This process is analogous to the manual review in COG construction. MCL clustering is based on weights between each pair of proteins, so to correct for differences in evolutionary distance the weights are normalized before running MCL.
Sun Nov 16
- Health, Medical and Life Extension Video Resources at HealthHaven.co m: AND BY HOMOLOGY, I MEAN, EVERYBODY MEANS, SIMILARITY BECAUSE OF COMMON DESCENT.
Sun Nov 9
- Science News / Unknotting Knot Theory
- YouTube - Genetics 101 Part 1: What are genes?: Animated guide to genes. IGCSE or AS level.
Fri Oct 31
Wed Oct 29
Mon Oct 27
If you would like to find additional social bookmark based links on the topic of we recommend the Open Tag Directory > Homology. If you would like to find related tags we recommend Tag Patterns > Homology
Off-site Homology Research Links
If you still need additional information on Homology then we suggest the following off-site resources. Please note, because these resources are off-site we cannot guarantee the accuracy or quality of any information.
Bioinformatic Topics
Everything you need to know about Bioinformatic
Bioinformatic
If you know the Bioinformatic Term Name use the links below to quickly jump to your desired focus.
Bookmark Us
The On Topic Network
This website is part of The On Topic Network.
Thank You
Bioinformatic.On-Topic.net was developed by Odin Metatech, Inc and runs on the Odin Assemble platform.
Best Viewed With
License
This work is licensed under Creative Commons.